Adverse Psychiatric Reactions Information Link
Promoting awareness of medicines that can harm mental health

Nivaquine Chloroquine Avloclor


Other names - Nivaquine, Aralen, Plaquenil

Active Substance Chloroquine Phosphate

Indication Therapy and prophylaxis of malaria.

Psychiatric Side effects
Convulsions and psychotic reactions including hallucinations (rare), anxiety, personality changes. 

When this medicine is used for short periods of time, side effects usually are rare. However, when it is used for a long time and/or in high doses, side effects are more likely to occur and may be serious.

Check with your doctor immediately if any of the following side effects occur:

Blurred vision; change in vision; loss of vision; feeling faint or lightheaded; mood or other mental changes; ringing or buzzing in ears or any loss of hearing; unusual tiredness or weakness

The above side effects may also occur or get worse after you stop taking this medicine

Chloroquine is very dangerous in overdose. It is rapidly absorbed from the gut and death often occurs within 2� hours of taking the drug. The therapeutic index for chloroquine is small and just doubling the normal dose of chloroquine can be fatal

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Medicine Information

If medication is found necessary for someone suffering a psychiatric adverse reaction, to keep the person calm for example, then the lowest dose possible should be used.

Reporting Adverse Drug Reactions (ADRs)
If you have suffered psychiatric adverse reactions please report them. There may be side effects not mentioned on the data sheets. You can request a list of drugs used pre surgery and during surgery. You should be given patient information for all drugs prescribed as you are discharged from hospital.

Please report Adverse Drug Reactions (ADRs) to:

UK Yellow Card Reporting for Patient and Health Professional reports of Adverse Drug Reactions

USA and worldwide to the Food and Drug Administration for Patients and Healthcare Professionals

Universal free, independent drug safety website - Rxisk

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